Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 4/20 | 0.35 |
| ▸ | PPARA | Q07869 | 4/20 | 0.35 |
| ▸ | LCLAT1 | Q6UWP7 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPY2R | P49146 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4640424 | 0.91 | KDM4E (0.39) | LMNAPPARGPPARAKMT2AKDM4E | |
| SCHEMBL4639814 | 0.91 | KDM4E (0.41) | LMNAKMT2AKDM4EHSD17B10MEN1 | |
| SCHEMBL4639512 | 0.91 | LMNA (0.38) | LMNAPPARGPPARAKMT2AKDM4E | |
| SCHEMBL4641121 | 0.91 | KDM4E (0.42) | LMNAKMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL5592687 | 0.89 | FPR2 (0.37) | LMNAKMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4641012 | 0.88 | TSHR (0.41) | LMNAPPARAKMT2AKDM4EALDH1A1 | |
| SCHEMBL5592764 | 0.87 | PARP1 (0.39) | LMNAPPARGPPARAKMT2AKDM4E | |
| SCHEMBL4639925 | 0.86 | KDM4E (0.41) | LMNAKMT2AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4639857 | 0.86 | S1PR1 (0.40) | LMNAKDM4EHSD17B10HPGDS1PR1 | |
| SCHEMBL4641231 | 0.86 | LMNA (0.36) | LMNADHODHPPARGPPARALCLAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007058338-A9 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMA CO LTD (JP) | 2007-11-01 | — | — | WO | disclosed |