Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14968337 | 1.00 | POLB (0.38) | POLBMEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL9656283 | 0.95 | POLB (0.37) | POLBMEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL7697029 | 0.93 | ALDH1A1 (0.38) | POLBMEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL14967907 | 0.93 | ALDH1A1 (0.38) | POLBMEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL14968098 | 0.87 | PPM1B (0.36) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL14968001 | 0.84 | LMNA (0.38) | POLBMEN1KMT2ASMN1; SMN2ATM | |
| SCHEMBL14967690 | 0.83 | PRKCA (0.39) | POLBSMN1; SMN2TSHRGAAMAPK1 | |
| SCHEMBL14967438 | 0.82 | CYP3A4 (0.40) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR | |
| SCHEMBL14967974 | 0.82 | PRKCA (0.40) | SMN1; SMN2TSHRGAAMAPK1 | |
| SCHEMBL14967412 | 0.81 | CYP3A4 (0.42) | MEN1KMT2ASMN1; SMN2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072506-A2 | POLYMORPHIC FORMS OF DOLASETRON MESYLATE AND PROCESSES THEREOF | USV LIMITED (IN) | 2007-06-28 | — | — | WO | disclosed |