Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.77 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 6/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.69 |
| ▸ | HTT | P42858 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALPL | P05186 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14605811 | 0.88 | MAPT (0.67) | ALDH1A1L3MBTL1LMNASMN1; SMN2TDP1 | |
| SCHEMBL10970735 | 0.79 | ALDH1A1 (0.84) | ALDH1A1L3MBTL1LMNASMN1; SMN2TDP1 | |
| SCHEMBL14605802 | 0.78 | ALPL (0.59) | ALDH1A1L3MBTL1LMNASMN1; SMN2TDP1 | |
| SCHEMBL17708397 | 0.77 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1LMNASMN1; SMN2TDP1 | |
| SCHEMBL9775196 | 0.76 | ALDH1A1 (0.53) | ALDH1A1L3MBTL1LMNASMN1; SMN2TDP1 | |
| SCHEMBL1612844 | 0.75 | POLB (0.73) | ALDH1A1L3MBTL1LMNASMN1; SMN2TDP1 | |
| SCHEMBL14606116 | 0.75 | ALDH1A1 (0.60) | ALDH1A1L3MBTL1LMNASMN1; SMN2TDP1 | |
| SCHEMBL14605822 | 0.74 | CPB1 (0.76) | ALDH1A1L3MBTL1LMNASMN1; SMN2TDP1 | |
| SCHEMBL14605816 | 0.74 | MAPT (0.80) | ALDH1A1L3MBTL1LMNASMN1; SMN2MEN1 | |
| SCHEMBL10672908 | 0.73 | ALDH1A1 (0.69) | ALDH1A1L3MBTL1LMNASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007029021-A1 | 1,5-SUBSTITUTED TETRAZOLES AS THERAPEUTIC COMPOUNDS | THE UNIVERSITY OF EDINBURGH (GB) | 2007-03-15 | — | — | WO | disclosed |