Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9775197 | 0.84 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1HTTNPSR1 | |
| SCHEMBL9775143 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2L3MBTL1HTTNPSR1 | |
| SCHEMBL17154293 | 0.83 | HSD11B1 (0.50) | ALDH1A1SMN1; SMN2L3MBTL1HTTNPC1 | |
| SCHEMBL9775210 | 0.83 | ALDH1A1 (0.61) | ALDH1A1SMN1; SMN2L3MBTL1HTTNPSR1 | |
| SCHEMBL9775192 | 0.81 | KAT6A (0.47) | ALDH1A1L3MBTL1HTTNPC1RAB9A | |
| SCHEMBL9872892 | 0.79 | SLC6A4 (0.43) | ALDH1A1SMN1; SMN2L3MBTL1HTTNPC1 | |
| SCHEMBL9872891 | 0.79 | SLC6A4 (0.43) | ALDH1A1SMN1; SMN2L3MBTL1HTTNPC1 | |
| SCHEMBL9775093 | 0.78 | NPC1 (0.57) | ALDH1A1SMN1; SMN2L3MBTL1HTTNPSR1 | |
| SCHEMBL5593134 | 0.76 | ALDH1A1 (0.77) | ALDH1A1SMN1; SMN2L3MBTL1HTTNPSR1 | |
| SCHEMBL21101969 | 0.75 | ALDH1A1 (0.45) | ALDH1A1SMN1; SMN2L3MBTL1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075339-A | Antiinflammatory agents, antiallergens | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-24 | — | — | US | claimed |
| US-5075339-A | Antiinflammatory agents, antiallergens | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-12-24 | — | — | US | disclosed |
| US-5039706-A | Antiinflammatory, antiallergenic agent | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-08-13 | — | — | US | disclosed |
| US-4948813-A | Benzylketone phospholipase A2 inhibitors | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-08-14 | — | — | US | disclosed |