Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | PDE2A | O00408 | 3/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.35 |
| ▸ | PDE6D | O43924 | 1/20 | 0.35 |
| ▸ | PDE6A | P16499 | 1/20 | 0.35 |
| ▸ | PDE6G | P18545 | 1/20 | 0.35 |
| ▸ | PDE6B | P35913 | 1/20 | 0.35 |
| ▸ | PDE6C | P51160 | 1/20 | 0.35 |
| ▸ | PDE6H | Q13956 | 1/20 | 0.35 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593404 | 0.79 | EGLN2 (0.42) | EGLN2DPP4PDE2APDE10APDE6D | |
| SCHEMBL3702960 | 0.78 | GRIA1 (0.38) | NPC1RAB9ACDK2 | |
| SCHEMBL3704252 | 0.76 | ADORA2A (0.41) | NPC1CCNE1CDK2MAP2K1 | |
| SCHEMBL5252606 | 0.75 | PDE2A (0.34) | EGLN2PDE2APDE10ARAB9ACCNE1 | |
| SCHEMBL1477252 | 0.75 | PDE2A (0.31) | PDE2AMAP2K1 | |
| SCHEMBL5239519 | 0.73 | PDE10A (0.38) | DPP4PDE2APDE10APDE6DPDE6A | |
| SCHEMBL5811587 | 0.71 | EGLN2 (0.36) | EGLN2DPP4RAB9AGSK3B | |
| SCHEMBL5593088 | 0.69 | EGLN2 (0.34) | EGLN2DPP4NISCHPTPN11 | |
| SCHEMBL361849 | 0.69 | MAP2K1 (0.39) | RAB9ACCNE1CDK2MAP2K1GSK3B | |
| SCHEMBL4491443 | 0.67 | GPR39 (0.45) | NPC1RAB9AGRM5MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007101871-A1 | SUBSTITUTED IMIDAZOLOPYRIMIDINES, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF FOR CONTROLLING PARASITIC FUNGI AND AGENTS CONTAINING THE LATTER | BASF SE (DE) | 2007-09-13 | — | — | WO | disclosed |