Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5811094 | 0.78 | EGLN2 (0.38) | EGLN2DPP4CRHR1CNR2KDM4E | |
| SCHEMBL5593135 | 0.71 | EGLN2 (0.40) | EGLN2DPP4RAB9AGSK3B | |
| SCHEMBL5252606 | 0.69 | PDE2A (0.34) | EGLN2KDM4EALDH1A1GLAGAA | |
| SCHEMBL5813202 | 0.68 | SMO (0.35) | EGLN2DPP4CRHR1CNR2ALDH1A1 | |
| SCHEMBL5324293 | 0.67 | KDM4E (0.43) | CRHR1KDM4EALDH1A1GLAGAA | |
| SCHEMBL940501 | 0.67 | GRIN2D (0.35) | CRHR1ALDH1A1 | |
| SCHEMBL3702960 | 0.66 | GRIA1 (0.38) | ALDH1A1RAB9A | |
| SCHEMBL5252895 | 0.66 | CCNE2 (0.35) | KDM4EALDH1A1GLAGAARAB9A | |
| SCHEMBL3704252 | 0.64 | ADORA2A (0.41) | KDM4EGAA | |
| SCHEMBL2796946 | 0.63 | ALDH1A1 (0.42) | CRHR1KDM4EALDH1A1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006122740-A2 | 7-AMINO-6-HETARYLIMIDAZOLO[1,2-A]PYRIMIDINE COMPOUNDS AND USE THEREOF FOR CONTROLLING HARMFUL FUNGI | BASF AKTIENGESELLSCHAFT (DE) | 2006-11-23 | — | — | WO | disclosed |