Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | CA7 | P43166 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16055176 | 0.89 | HSD17B2 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3629768 | 0.86 | NOTUM (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL18077316 | 0.82 | CA12 (0.48) | CA12CA1CA2CA7CA9 | |
| SCHEMBL22032172 | 0.81 | HSD17B2 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2645488 | 0.81 | HSD17B2 (0.51) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2541425 | 0.81 | CA12 (0.49) | CA12CA1CA2CA7CA9 | |
| SCHEMBL670686 | 0.80 | HSD17B2 (0.65) | CA12CA1CA2CA7CA9 | |
| SCHEMBL16742132 | 0.79 | ALDH1A1 (0.42) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11354751 | 0.78 | THRA (0.62) | HPGDGAAMAPTALDH1A1KMT2A | |
| SCHEMBL2818575 | 0.77 | LMNA (0.56) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |