Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 6/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602261 | 0.86 | HTT (0.43) | TSHRHTTPOLBMAPTMEN1 | |
| SCHEMBL4551944 | 0.86 | NR1H4 (0.46) | RXFP1NR1H4PPARGPPARATSHR | |
| SCHEMBL5593328 | 0.83 | RXFP1 (0.43) | RXFP1NR1H4PPARGPPARATSHR | |
| SCHEMBL4411700 | 0.80 | MEN1 (0.43) | RXFP1NR1H4PPARGPPARATSHR | |
| SCHEMBL4407836 | 0.80 | NR1H4 (0.45) | RXFP1NR1H4PPARGPPARAHTT | |
| SCHEMBL5592971 | 0.80 | RXFP1 (0.42) | RXFP1NR1H4PPARGPPARATSHR | |
| SCHEMBL5592986 | 0.78 | RXFP1 (0.41) | RXFP1NR1H4PPARGPPARATSHR | |
| SCHEMBL5593295 | 0.78 | NR1H4 (0.47) | RXFP1NR1H4PPARGPPARATSHR | |
| SCHEMBL4414236 | 0.78 | NAMPT (0.43) | RXFP1NR1H4PPARGPPARATSHR | |
| SCHEMBL4413480 | 0.77 | RAF1 (0.45) | RXFP1NR1H4NPC1DHODHMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |