Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | PDE2A | O00408 | 1/20 | 0.39 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.39 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5604308 | 0.80 | BRAF (0.34) | ALDH1A1KMT2ATSHRMEN1CYP3A4 | |
| SCHEMBL5593509 | 0.80 | GAA (0.44) | ALDH1A1TDP1KMT2ATSHRMEN1 | |
| SCHEMBL5593513 | 0.80 | GAA (0.44) | ALDH1A1TDP1KMT2ATSHRMEN1 | |
| SCHEMBL14473328 | 0.77 | ALDH1A1 (0.43) | ALDH1A1TDP1KMT2ATSHRMEN1 | |
| Hydrochloric Acid SCHEMBL5593031 | 0.76 | ALDH1A1 (0.42) | ALDH1A1TDP1KMT2ATSHRMEN1 | |
| SCHEMBL5593372 | 0.75 | KMT2A (0.42) | ALDH1A1TDP1KMT2ATSHRMEN1 | |
| SCHEMBL5593366 | 0.75 | KMT2A (0.42) | ALDH1A1TDP1KMT2ATSHRMEN1 | |
| SCHEMBL5593426 | 0.72 | GABRA1 (0.43) | ALDH1A1TDP1KMT2ATSHRMEN1 | |
| SCHEMBL11765352 | 0.72 | ALDH1A1 (0.53) | ALDH1A1TDP1KMT2ATSHRMEN1 | |
| SCHEMBL11765362 | 0.72 | ALDH1A1 (0.53) | ALDH1A1TDP1KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |