Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593366 | 1.00 | KMT2A (0.42) | KMT2APOLBMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL5604301 | 0.82 | POLB (0.45) | POLBSMN1; SMN2CYP1A2ALDH1A1LMNA | |
| SCHEMBL5593509 | 0.79 | GAA (0.44) | KMT2APOLBMEN1ALDH1A1TSHR | |
| SCHEMBL5593513 | 0.79 | GAA (0.44) | KMT2APOLBMEN1ALDH1A1TSHR | |
| SCHEMBL14473328 | 0.76 | ALDH1A1 (0.43) | KMT2APOLBMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5593369 | 0.75 | ALDH1A1 (0.40) | KMT2APOLBMEN1SMN1; SMN2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL5593031 | 0.75 | ALDH1A1 (0.42) | KMT2APOLBMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5593426 | 0.71 | GABRA1 (0.43) | KMT2APOLBMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL6408045 | 0.71 | MAPT (0.52) | KMT2APOLBMEN1SMN1; SMN2ALDH1A1 | |
| SCHEMBL5604172 | 0.70 | MAPT (0.49) | KMT2APOLBMEN1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |