Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TEK | Q02763 | 2/20 | 0.44 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.40 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593449 | 0.81 | CSF1R (0.57) | CSF1RBRAF | |
| SCHEMBL5593400 | 0.77 | RAF1 (0.46) | TEKCSF1RHIF1AEPAS1LMNA | |
| SCHEMBL5593421 | 0.74 | L3MBTL1 (0.43) | LMNARAB9AALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5593307 | 0.73 | MAPK14 (0.51) | CSF1RCYP2C9BRAF | |
| SCHEMBL4565686 | 0.72 | RAF1 (0.51) | TEKCSF1RBRAF | |
| SCHEMBL4417402 | 0.70 | TEK (0.54) | TEKCSF1RHIF1AEPAS1DDR1 | |
| SCHEMBL4417493 | 0.69 | TEK (0.46) | TEKBRAF | |
| SCHEMBL5622327 | 0.69 | RAF1 (0.48) | TEKCSF1RRAB9ANPC1BRAF | |
| SCHEMBL5592959 | 0.68 | MAPK14 (0.53) | TP53SMN1; SMN2CYP2C9BRAF | |
| SCHEMBL14473325 | 0.67 | NPC1 (0.42) | TEKCSF1RLMNARAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |