Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | RAF1 | P04049 | 3/20 | 0.41 |
| ▸ | BRAF | P15056 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593368 | 0.80 | GAA (0.43) | L3MBTL1SMN1; SMN2GAABRAFMEN1 | |
| SCHEMBL4420074 | 0.79 | RAF1 (0.49) | L3MBTL1MAPK14HSD17B10RAF1BRAF | |
| SCHEMBL5593421 | 0.77 | L3MBTL1 (0.43) | L3MBTL1MAPK14HSD17B10SMN1; SMN2GAA | |
| SCHEMBL5593400 | 0.74 | RAF1 (0.46) | SMN1; SMN2RAF1BRAFNPC1RAB9A | |
| SCHEMBL5593295 | 0.69 | NR1H4 (0.47) | SMN1; SMN2GAAMEN1KMT2APOLB | |
| SCHEMBL1600543 | 0.69 | MAPK14 (0.71) | MAPK14RAF1BRAFLCK | |
| SCHEMBL4413480 | 0.69 | RAF1 (0.45) | MAPK14SMN1; SMN2GAARAF1BRAF | |
| SCHEMBL4551800 | 0.69 | MEN1 (0.46) | SMN1; SMN2GAARAF1MEN1KMT2A | |
| SCHEMBL14473322 | 0.69 | MEN1 (0.44) | MAPK14SMN1; SMN2GAARAF1BRAF | |
| SCHEMBL4415213 | 0.69 | RAF1 (0.45) | MAPK14RAF1BRAFMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |