Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.46 |
| ▸ | KAT7 | O95251 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1861675 | 1.00 | RAB9A (0.53) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL1867619 | 0.91 | GAA (0.49) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL3617205 | 0.91 | GAA (0.49) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL1870934 | 0.89 | GAA (0.48) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL4303570 | 0.88 | GAA (0.47) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL3878807 | 0.88 | GAA (0.47) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL31602900 | 0.88 | RORC (0.46) | RAB9AGAAMEN1KMT2AMAPT | |
| SCHEMBL12991579 | 0.87 | ALDH1A1 (0.51) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL1865320 | 0.87 | HSD11B1 (0.52) | RAB9AGAAALDH1A1MEN1KMT2A | |
| SCHEMBL31358021 | 0.86 | ALDH1A1 (0.53) | RAB9AGAAALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007117560-A2 | PIPERIDINE AND MORPHOLINE RENIN INHIBITORS | VITAE PHARMACEUTICALS, INC. (US) | 2007-10-18 | — | — | WO | disclosed |