Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 18/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 18/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 18/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.41 |
| ▸ | REN | P00797 | 2/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5593346 | 0.90 | SLC6A2 (0.40) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL4754589 | 0.89 | REN (0.41) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL4755799 | 0.89 | REN (0.41) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL5593564 | 0.83 | SLC6A2 (0.34) | SLC6A2SLC6A4SLC6A3REN | |
| SCHEMBL5613173 | 0.82 | SLC6A2 (0.36) | SLC6A2SLC6A4SLC6A3REN | |
| SCHEMBL3879197 | 0.79 | SLC6A2 (0.38) | SLC6A2SLC6A4SLC6A3KCNH2CYP2D6 | |
| SCHEMBL5593301 | 0.78 | SLC6A2 (0.35) | SLC6A2SLC6A4KCNH2CYP2D6REN | |
| SCHEMBL3881258 | 0.78 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3REN | |
| SCHEMBL5592047 | 0.77 | REN (0.34) | SLC6A2SLC6A4SLC6A3REN | |
| SCHEMBL5612896 | 0.77 | REN (0.33) | SLC6A2SLC6A4SLC6A3KCNH2REN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007110627-A2 | 3,7-DIAMINO-10H-PHENOTHIAZINE SALTS AND THEIR USE | WISTA LABORATORIES LTD. (SG) | 2007-10-04 | — | — | WO | disclosed |