Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.33 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3548162 | 0.72 | TP53 (0.32) | — | |
| SCHEMBL10435320 | 0.71 | SLC6A2 (0.58) | ESR1ESR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8100227 | 0.71 | ESR1 (0.61) | ESR1ESR2SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL2011912 | 0.67 | MAPK1 (0.36) | CYP3A4CSNK1EALDH1A1 | |
| SCHEMBL18043744 | 0.65 | SLC6A4 (0.32) | SLC6A4 | |
| SCHEMBL2067545 | 0.65 | LMNA (0.41) | — | |
| SCHEMBL28163887 | 0.65 | ESR1 (0.53) | ESR1ESR2SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL22721261 | 0.65 | ESR1 (0.49) | ESR1ESR2SIGMAR1SLC6A2SLC6A4 | |
| SCHEMBL9543263 | 0.65 | SIGMAR1 (0.48) | SIGMAR1SLC6A2SLC6A4SLC6A3TAAR1 | |
| SCHEMBL1047441 | 0.65 | SIGMAR1 (0.48) | SIGMAR1SLC6A2SLC6A4SLC6A3TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1441724-B1 | METHODS OF INCREASING ENDOGENOUS TESTOSTERONE LEVELS | APPLIED RESEARCH SYSTEMS (AN) | 2007-09-05 | — | — | EP | disclosed |