Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 6/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.46 |
| ▸ | IAPP | P10997 | 4/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4312373 | 0.88 | ALOX5 (0.53) | GABRA1GABRB2IAPPALOX5PTGS2 | |
| SCHEMBL17220630 | 0.86 | ALOX5 (0.60) | IAPPALOX5PTGS2ELANECTSG | |
| SCHEMBL674691 | 0.84 | GABRA1 (0.64) | GABRA1GABRB2IAPPALOX5PTGS2 | |
| SCHEMBL8379462 | 0.83 | ALDH1A1 (0.45) | GABRA1GABRB2IAPPALOX5PTGS2 | |
| SCHEMBL4105394 | 0.83 | GABRA1 (0.70) | GABRA1GABRB2IAPPMMP2 | |
| SCHEMBL31376379 | 0.82 | GABRA1 (0.61) | GABRA1GABRB2IAPPALOX5PTGS2 | |
| SCHEMBL10762848 | 0.81 | HMGB1 (0.56) | MMP2HMGB1 | |
| SCHEMBL14895143 | 0.81 | MMP2 (0.41) | GABRA1GABRB2IAPPALOX5PTGS2 | |
| Bromide SCHEMBL4967570 | 0.81 | GABRA1 (0.67) | GABRA1GABRB2IAPPMMP2DAO | |
| SCHEMBL27984845 | 0.79 | FOLH1 (0.41) | GABRA1GABRB2IAPPALOX5PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9957241-B2 | Aromatic diamine, an intermediate therefor, a method for producing the aromatic diamine, and a method for producing the intermediate therefor | SEIKA CORPORATION (JP) | 2018-05-01 | — | — | US | disclosed |
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | SEIKA CORPORATION (JP) | 2018-03-22 | — | — | US | disclosed |
| US-9816018-B2 | Polyurethane sealant based on poly(butylene oxide) polyols for glass sealing | DOW GLOBAL TECHNOLOGIES LLC (US) | 2017-11-14 | — | — | US | disclosed |
| CN-107001629-A | Resin and photosensitive polymer combination | 东丽株式会社 | 2017-08-01 | — | — | CN | disclosed |
| EP-2738208-B1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | SHIKOKU CHEM (JP) | 2017-07-19 | — | — | EP | disclosed |
| US-9560848-B2 | Method and compositions for biofouling deterrence | CLEMSON UNIVERSITY (US) | 2017-02-07 | — | — | US | disclosed |
| US-20160002512-A1 | Polyurethane Sealant Based on Poly(Butylene Oxide) Polyols for Glass Sealing | DOW GLOBAL TECHNOLOGIES LLC | 2016-01-07 | — | — | US | disclosed |
| CN-103703071-B | Coupling agent for rubber/carbon black and rubber composition for tire containing the same | SHIKOKU CHEMICALS CORP. (JP) | 2015-12-09 | — | — | CN | disclosed |
| US-9200145-B2 | Coupling agent for rubber/carbon black, and rubber composition containing same for use in tires | SHIKOKU CHEMICALS CORPORATION (JP) | 2015-12-01 | — | — | US | disclosed |
| US-20140155541-A1 | COUPLING AGENT FOR RUBBER/CARBON BLACK, AND RUBBER COMPOSITION CONTAINING SAME FOR USE IN TIRES | SHIKOKU CHEMICALS CORPORATION (JP) | 2014-06-05 | — | — | US | disclosed |
| EP-0896531-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-02-17 | — | — | EP | disclosed |
| US-5780483-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORPORATION (US) | 1998-07-14 | — | — | US | disclosed |
| EP-0809492-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-12-03 | — | — | EP | disclosed |
| WO-1997029743-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1997-08-21 | — | — | WO | disclosed |
| WO-1996025157-A1 | IL-8 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 1996-08-22 | — | — | WO | disclosed |
| EP-0253340-B1 | ALKYL-SUBSTITUTED BENZOXAZINORIFAMYCIN DERIVATIVE, PROCESS FOR PREPARING THE SAME AND ANTIBACTERIAL AGENT CONTAINING THE SAME | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1993-09-29 | — | — | EP | disclosed |
| CN-1018833-B | Alkyl substituted benzoxazinorifamycin derivatives | KANEGAFUCHI CHEMICAL IND (JP) | 1992-10-28 | — | — | CN | disclosed |
| US-4859661-A | Alkyl-substituted benzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1989-08-22 | — | — | US | disclosed |
| CN-87104870-A | Benzoxazinnorifamyciderivative derivative, its preparation method that alkyl replaces and contain the antiseptic-germicide of this derivative | — | 1988-02-17 | — | — | CN | disclosed |
| EP-0253340-A1 | Alkyl-substituted benzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same | KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1988-01-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180079732-A1 | AROMATIC DIAMINE, AN INTERMEDIATE THEREFOR, A METHOD FOR PRODUCING THE AROMATIC DIAMINE, AND A METHOD FOR PRODUCING THE INTERMEDIATE THEREFOR | WEE1, WEE2, WASF2 | GABRA1 409/4885GABRB2 640/4885IAPP 1679/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.