SCHEMBL5595237

SCHEMBL5595237

CCCCCCCC/C=C\CCCCCCCC(=O)OC[C@@H](CO)OCCOC1CCCCO1

nearest known ligand 0.56

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 3/20 0.55
PRKCE Q02156 2/20 0.55
PRKCQ Q04759 2/20 0.55
PRKCD Q05655 2/20 0.55
CNR1 P21554 1/20 0.53
CNR2 P34972 1/20 0.53
DGKA P23743 1/20 0.49
LPAR1 Q92633 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5595866 0.89 ENPP2 (0.50) PRKCAPRKCEPRKCQPRKCDLPAR1
SCHEMBL31615051 0.88 PRKCA (0.58) PRKCAPRKCEPRKCQPRKCD
SCHEMBL9464928 0.84 MGLL (0.46) CNR1DGKA
SCHEMBL27160928 0.84 MGLL (0.46) CNR1DGKA
SCHEMBL9464941 0.84 MGLL (0.46) CNR1DGKA
SCHEMBL30028349 0.84 MGLL (0.46) CNR1DGKA
SCHEMBL5595684 0.82 LPAR1 (0.38) PRKCAPRKCEPRKCQPRKCDCNR1
SCHEMBL10492119 0.82 PRKCA (0.76) PRKCAPRKCEPRKCQPRKCDCNR1
SCHEMBL7557200 0.82 PRKCA (0.76) PRKCAPRKCEPRKCQPRKCDCNR1
SCHEMBL7557194 0.82 PRKCA (0.76) PRKCAPRKCEPRKCQPRKCDCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070123492-A1 Analogs of lysophosphatidic acid and methods of making and using thereof NATIONAL INSTITUTES OF HEALTH - DIRECTOR DEITR 2007-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070123492-A1 Analogs of lysophosphatidic acid and methods of making and using thereof LPAR4, LPAR2, LPAR5 PRKCA 736/4885PRKCE 841/4885PRKCQ 920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.