Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | DGKA | P23743 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30028349 | 1.00 | MGLL (0.46) | MGLLMEN1KMT2AFAAHALDH1A1 | |
| SCHEMBL9464928 | 1.00 | MGLL (0.46) | MGLLMEN1KMT2AFAAHALDH1A1 | |
| SCHEMBL8920889 | 0.93 | DGKA (0.51) | MEN1KMT2ADGKA | |
| SCHEMBL31615051 | 0.89 | PRKCA (0.58) | ALDH1A1 | |
| SCHEMBL10771687 | 0.87 | MEN1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL11345708 | 0.87 | MEN1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL7597634 | 0.87 | MEN1 (0.44) | MEN1KMT2AALDH1A1 | |
| SCHEMBL19331817 | 0.86 | MEN1 (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL31614996 | 0.86 | MEN1 (0.46) | MEN1KMT2AALDH1A1 | |
| SCHEMBL5595237 | 0.84 | PRKCA (0.55) | CNR1DGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5242945-A | Antiinflammatory | AMERICAN HOME PRODUCTS CORPORATION (US) | 1993-09-07 | — | — | US | disclosed |
| EP-0508690-A1 | Tetronic and thiotetronic acid derivatives | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-10-14 | — | — | EP | disclosed |