Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 8/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 8/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.36 |
| ▸ | MLYCD | O95822 | 6/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4880561 | 0.81 | NR1H2 (0.42) | NR1H2NR1H3MLYCD | |
| SCHEMBL5595300 | 0.79 | MLYCD (0.41) | NR1H2NR1H3MLYCDSMN1; SMN2 | |
| SCHEMBL4419153 | 0.77 | MLYCD (0.41) | NR1H2NR1H3MLYCDSMN1; SMN2 | |
| SCHEMBL4429385 | 0.75 | NR1H3 (0.37) | NR1H2NR1H3MLYCDSMN1; SMN2RORC | |
| SCHEMBL4884879 | 0.74 | NR1H2 (0.46) | NR1H2NR1H3MLYCD | |
| SCHEMBL7248333 | 0.68 | GFER (0.46) | DGAT1 | |
| SCHEMBL9145018 | 0.68 | RAB9A (0.48) | — | |
| SCHEMBL1436365 | 0.67 | NPBWR1 (0.37) | SMN1; SMN2 | |
| SCHEMBL12775761 | 0.66 | POLB (0.38) | NR1H2NR1H3 | |
| SCHEMBL4883425 | 0.66 | MLYCD (0.44) | NR1H2NR1H3DGAT1MLYCDRORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279477-B2 | Malonyl-CoA decarboxylase inhibitors useful as metabolic modulators | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2007-10-09 | — | — | US | claimed |