Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 7/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | SRC | P12931 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596124 | 0.74 | LMNA (0.35) | TRPA1LMNAAOC3KDM4EL3MBTL1 | |
| SCHEMBL5595943 | 0.71 | TRPA1 (0.35) | TRPA1LMNAAOC3KDM4EL3MBTL1 | |
| SCHEMBL20568160 | 0.69 | DPP4 (0.39) | LMNAHTR2ATAAR1CYP2D6SRC | |
| SCHEMBL5596219 | 0.68 | ALDH1A1 (0.37) | TRPA1LMNAKDM4EL3MBTL1HTR2A | |
| SCHEMBL7935090 | 0.66 | LMNA (0.39) | TRPA1LMNAKDM4EL3MBTL1HTR2A | |
| SCHEMBL5596091 | 0.64 | LMNA (0.42) | LMNAAOC3KDM4EHTR2ATAAR1 | |
| SCHEMBL5596479 | 0.63 | ALDH1A1 (0.35) | LMNAAOC3KDM4EL3MBTL1CYP2D6 | |
| SCHEMBL5613303 | 0.63 | DPP4 (0.33) | LMNAKDM4EHTR2ATAAR1CYP2D6 | |
| SCHEMBL3454935 | 0.63 | TRPA1 (0.38) | TRPA1LMNAKDM4EL3MBTL1HTR2A | |
| SCHEMBL434195 | 0.62 | SRC (0.42) | LMNACYP2D6SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |