Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ILK | Q13418 | 2/20 | 0.52 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 5/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | SMARCA2 | P51531 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | THPO | P40225 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7144576 | 0.85 | ILK (0.50) | ILKIRAK4MGLLLTA4HACP1 | |
| SCHEMBL5596942 | 0.80 | ILK (0.51) | ILKIRAK4TP53TSHRRAB9A | |
| SCHEMBL5596256 | 0.79 | NPC1 (0.54) | ILKTP53CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5596406 | 0.78 | ILK (0.51) | ILKTP53TSHRRAB9ASMN1; SMN2 | |
| SCHEMBL5596758 | 0.78 | QPCT (0.41) | ILKIRAK4TP53TSHRMAPK1 | |
| SCHEMBL5596674 | 0.76 | NPC1 (0.44) | ILKMGLLLTA4HCYP1A2CYP3A4 | |
| SCHEMBL5596937 | 0.76 | ILK (0.53) | ILKIRAK4MGLLTP53CYP1A2 | |
| SCHEMBL5596418 | 0.76 | NPC1 (0.44) | ILKMGLLTP53CYP1A2CYP3A4 | |
| SCHEMBL5596495 | 0.76 | LTA4H (0.39) | ILKLTA4HTP53TSHRMAPK1 | |
| SCHEMBL5596939 | 0.76 | NPC1 (0.44) | ILKMGLLTP53CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1696909-B1 | BENZOTHIAZOLE DERIVATIVES FOR THE TREATMENT OF DIABETES | SERONO LAB (CH) | 2007-11-14 | — | — | EP | claimed |