Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | FADS1 | O60427 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596568 | 0.80 | ESR2 (0.42) | TSHRALOX5ESR2ALDH1A1MAPK1 | |
| SCHEMBL5596874 | 0.78 | TDP1 (0.52) | TSHRESR2ALDH1A1POLBHSD17B10 | |
| SCHEMBL5595981 | 0.77 | ALDH1A1 (0.42) | TSHRALOX5ESR2ALDH1A1HSD17B10 | |
| SCHEMBL29851249 | 0.77 | ALDH1A1 (0.46) | TSHRALOX5ALDH1A1CYP3A4TDP1 | |
| SCHEMBL197486 | 0.77 | ALDH1A1 (0.46) | TSHRALOX5ALDH1A1CYP3A4TDP1 | |
| SCHEMBL5596301 | 0.76 | ALDH1A1 (0.44) | TSHRALOX5ESR2ALDH1A1MAPK1 | |
| SCHEMBL9854467 | 0.76 | TDP1 (0.57) | TSHRESR2ALDH1A1CYP3A4TDP1 | |
| SCHEMBL5596888 | 0.74 | TSHR (0.35) | TSHRALOX5ESR2 | |
| SCHEMBL5596221 | 0.74 | CYP1A1 (0.44) | TSHRFADS1 | |
| SCHEMBL5596208 | 0.74 | CA2 (0.47) | TSHRALOX5ESR2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |