Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596542 | 0.81 | ALOX15 (0.45) | ESR2ALOX15HSD17B10ALDH1A1TRPA1 | |
| SCHEMBL5596301 | 0.80 | ALDH1A1 (0.44) | ESR2ALOX15HSD17B10ALDH1A1ALOX5 | |
| SCHEMBL5596286 | 0.80 | TSHR (0.42) | ESR2ALOX15HSD17B10ALDH1A1ALOX5 | |
| SCHEMBL5596528 | 0.79 | ESR2 (0.38) | ESR2ALDH1A1ALOX5MAPTLMNA | |
| SCHEMBL7189644 | 0.78 | ALOX15 (0.45) | ESR2ALOX15HSD17B10ALDH1A1TRPA1 | |
| SCHEMBL6438829 | 0.76 | TRPA1 (0.56) | ALOX15HSD17B10ALDH1A1TRPA1HPGD | |
| SCHEMBL5595981 | 0.75 | ALDH1A1 (0.42) | ESR2HSD17B10ALDH1A1ALOX5TRPA1 | |
| SCHEMBL197486 | 0.72 | ALDH1A1 (0.46) | ALDH1A1ALOX5MEN1KMT2AMAPT | |
| SCHEMBL29851249 | 0.72 | ALDH1A1 (0.46) | ALDH1A1ALOX5MEN1KMT2AMAPT | |
| SCHEMBL5596412 | 0.71 | CFTR (0.34) | ALDH1A1ALOX5HPGDMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |