Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | PNMT | P11086 | 2/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | AGXT | P21549 | 2/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.37 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.37 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | PLAU | P00749 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29851249 | 1.00 | ALDH1A1 (0.46) | ALDH1A1TSHRCYP3A4TDP1PNMT | |
| SCHEMBL9854467 | 0.93 | TDP1 (0.57) | ALDH1A1TSHRCYP3A4TDP1PNMT | |
| SCHEMBL9624166 | 0.85 | MEN1 (0.41) | ALDH1A1TSHRCYP3A4TDP1MAPT | |
| SCHEMBL9624369 | 0.82 | CYP19A1 (0.47) | ALDH1A1CYP3A4MEN1HTTKMT2A | |
| SCHEMBL31561762 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP3A4TDP1PNMT | |
| SCHEMBL2155168 | 0.81 | ALDH1A1 (0.44) | ALDH1A1TSHRCYP3A4TDP1PNMT | |
| SCHEMBL11004135 | 0.80 | SIGMAR1 (0.42) | CYP3A4TDP1PNMTTAAR1MAPT | |
| SCHEMBL2154288 | 0.79 | ALDH1A1 (0.42) | ALDH1A1TSHRCYP3A4TDP1PNMT | |
| SCHEMBL11454863 | 0.77 | PNMT (0.41) | ALDH1A1TSHRCYP3A4TDP1PNMT | |
| SCHEMBL5596286 | 0.77 | TSHR (0.42) | ALDH1A1TSHRCYP3A4TDP1ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 421 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119143707-B | Spiral-2 (3H) -furanone molecule and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2025-01-28 | — | — | CN | claimed |
| CN-119241533-A | Preparation method of tetrahydro-gamma-carboline | 湖北科技学院 | 2025-01-03 | — | — | CN | claimed |
| CN-119143707-A | Spiral-2 (3H) -furanone molecule and preparation method and application thereof | 山东第一医科大学(山东省医学科学院) | 2024-12-17 | — | — | CN | claimed |
| CN-119100969-A | Preparation method of C2-site alkylated indole compound | 湖北科技学院 | 2024-12-10 | — | — | CN | claimed |
| US-12090473-B2 | Catalyst compositions and hydroformylation processes | DOW TECHNOLOGY INVESTMENTS LLC (US) | 2024-09-17 | — | — | US | claimed |
| WO-2022244969-A1 | METHOD FOR PREPARING METHYLENE LACTONE-BASED COMPOUND | 주식회사 자경케미칼 | 2022-11-24 | — | — | WO | claimed |
| CN-110359097-B | Method for obtaining On-DNA aromatic hydrocarbon compound through Suzuki coupling reaction in construction of DNA coding compound library | 上海药明康德新药开发有限公司 | 2022-09-20 | — | — | CN | claimed |
| CN-110331447-B | Method for preparing On-DNA aryl alkyne compound in construction of DNA coding compound library | 上海药明康德新药开发有限公司 | 2022-05-27 | — | — | CN | claimed |
| CN-110079867-B | On-DNA wittig reaction method in DNA coding compound library and prepared On-DNA olefin compound | 上海药明康德新药开发有限公司 | 2022-01-04 | — | — | CN | claimed |
| CN-112830905-A | Benzo [ f ] indeno [1,2-d ] [1,2] thiazepine 5-oxy series compounds having a quaternary ring system structure | 江西师范大学 | 2021-05-25 | — | — | CN | claimed |
| WO-1998007724-A1 | PROCESS FOR THE PREPARATION OF 7-ALKOXYALKYL-1,2,4-TRIAZOLO[1,5-A] PYRIMIDINE DERIVATIVES | KNOLL AKTIENGESELLSCHAFT (DE) | 1998-02-26 | — | — | WO | claimed |
| EP-0449296-B1 | Palladium catalyzed carboalkoxylation of butadiene | DU PONT (US) | 1994-09-14 | — | — | EP | claimed |
| EP-0449296-A1 | Palladium catalyzed carboalkoxylation of butadiene | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-10-02 | — | — | EP | claimed |
| EP-0194707-B1 | PROCESS FOR THE HYDROCARBOXYLATION OF ACETYLENICALLY UNSATURATED COMPOUNDS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-09-18 | — | — | EP | claimed |
| EP-0271145-B1 | PROCESS FOR THE CARBONYLATION OF CONJUGATED DIENES | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1991-08-21 | — | — | EP | claimed |
| US-5026901-A | Producing alkyl pentenoate | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-06-25 | — | — | US | claimed |
| US-4824817-A | Catalyst for the carbonylation of conjugated dienes | SHELL OIL COMPANY (US) | 1989-04-25 | — | — | US | claimed |
| EP-0271145-A2 | Process for the carbonylation of conjugated dienes | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1988-06-15 | — | — | EP | claimed |
| US-4731202-A | Process for the hydrocarboxylation of acetylenically unsaturated compounds | SHELL OIL COMPANY (US) | 1988-03-15 | — | — | US | claimed |
| EP-0194707-A2 | Process for the hydrocarboxylation of acetylenically unsaturated compounds | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1986-09-17 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12090473-B2 | Catalyst compositions and hydroformylation processes | NUDT1, DHPS, NUDT5 | ALDH1A1 1201/4885TSHR 4279/4885CYP3A4 1072/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.