Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2549706 | 0.70 | CRHR1 (0.30) | — | |
| SCHEMBL8346863 | 0.69 | RAPGEF4 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11785341 | 0.68 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL301709 | 0.68 | RAPGEF4 (0.43) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL11035532 | 0.67 | SLC6A2 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL3530399 | 0.67 | SLC6A2 (0.39) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| Isopropyl Alcohol SCHEMBL11909735 | 0.67 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAGAAMAPT | |
| Bromide SCHEMBL3679642 | 0.66 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| Iodide SCHEMBL9662368 | 0.66 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA | |
| Silver SCHEMBL31010581 | 0.66 | RAPGEF4 (0.41) | RAPGEF4ALDH1A1KDM4ELMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |