Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 3/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596520 | 0.90 | TP53 (0.33) | PCSK9PTGS2CES2CES1LMNA | |
| SCHEMBL5596619 | 0.86 | PCSK9 (0.36) | PCSK9PTGS2CES2CES1LTA4H | |
| Phenol SCHEMBL10754763 | 0.77 | CA12 (0.50) | PCSK9PTGS2LTA4HEGFRLMNA | |
| Biphenyl SCHEMBL1123907 | 0.76 | ALDH1A1 (0.45) | PCSK9LTA4HHDAC3 | |
| Benzoic Acid SCHEMBL27772864 | 0.76 | TSHR (0.56) | CES2CES1NAAA | |
| SCHEMBL5596690 | 0.75 | TP53 (0.32) | PCSK9PTGS2CES2CES1LMNA | |
| Benzene SCHEMBL27714186 | 0.75 | TSHR (0.40) | PCSK9LTA4HEGFRLMNA | |
| SCHEMBL118540 | 0.75 | TSHR (0.40) | PCSK9CES2CES1EGFRLMNA | |
| Toluene SCHEMBL3671880 | 0.74 | TSHR (0.52) | PCSK9PTGS2CES2CES1LTA4H | |
| SCHEMBL28411177 | 0.74 | CES2 (0.39) | PCSK9PTGS2CES2CES1LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |