Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 3/20 | 0.32 |
| ▸ | CES1 | P23141 | 3/20 | 0.32 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5596433 | 0.90 | PCSK9 (0.37) | CES2CES1PCSK9LMNAPTGS2 | |
| SCHEMBL5596690 | 0.84 | TP53 (0.32) | TP53CES2CES1PCSK9LMNA | |
| SCHEMBL118540 | 0.80 | TSHR (0.40) | CES2CES1PCSK9LMNAALDH1A1 | |
| SCHEMBL6669960 | 0.77 | TSHR (0.38) | CES2CES1PCSK9LMNAALDH1A1 | |
| SCHEMBL4631055 | 0.77 | TSHR (0.38) | CES2CES1PCSK9LMNAALDH1A1 | |
| SCHEMBL9622609 | 0.77 | TSHR (0.38) | CES2CES1PCSK9LMNAALDH1A1 | |
| SCHEMBL5596457 | 0.76 | ALDH1A1 (0.34) | MEN1ALDH1A1GAAPKMTSHR | |
| SCHEMBL3481968 | 0.76 | TP53 (0.54) | TP53MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL5596619 | 0.75 | PCSK9 (0.36) | CES2CES1PCSK9LMNAPTGS2 | |
| Benzoic Acid SCHEMBL31683063 | 0.73 | TSHR (0.64) | TP53CES2CES1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7279537-B2 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-10-09 | — | — | US | disclosed |
| US-20060229195-A1 | Transition metal complexes and polymerization catalysts | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-12 | — | — | US | disclosed |
| EP-1557423-A1 | TRANSITION METAL COMPLEXES AND POLYMERIZATION CATALYSTS | Sumitomo Chemical Company, Limited (JP) | 2005-07-27 | — | — | EP | disclosed |