SCHEMBL118540

SCHEMBL118540

O[SiH](c1ccccc1)c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.40
DAO P14920 1/20 0.40
NAPRT Q6XQN6 1/20 0.40
CA4 P22748 3/20 0.39
CA14 Q9ULX7 3/20 0.39
TDP1 Q9NUW8 3/20 0.39
CA12 O43570 2/20 0.39
CA2 P00918 2/20 0.39
CA3 P07451 2/20 0.39
CA1 P00915 1/20 0.39
GLA P06280 1/20 0.39
CA9 Q16790 1/20 0.39
ALDH1A1 P00352 5/20 0.35
CES2 O00748 3/20 0.33
CES1 P23141 3/20 0.33
ALOX15 P16050 2/20 0.33
CA5A P35218 2/20 0.33
CA5B Q9Y2D0 2/20 0.33
LMNA P02545 2/20 0.33
IDO1 P14902 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6669960 0.97 TSHR (0.38) TSHRDAONAPRTCA4CA14
SCHEMBL4631055 0.97 TSHR (0.38) TSHRDAONAPRTCA4CA14
SCHEMBL9622609 0.97 TSHR (0.38) TSHRDAONAPRTCA4CA14
SCHEMBL5596457 0.84 ALDH1A1 (0.34) TSHRDAONAPRTTDP1ALDH1A1
SCHEMBL3481591 0.84 ACHE (0.48) TSHRTDP1ALDH1A1CES2CES1
SCHEMBL5596520 0.80 TP53 (0.33) TSHRALDH1A1CES2CES1LMNA
Phosphoric Acid SCHEMBL28124675 0.80 CA2 (0.36) TSHRDAONAPRTCA4CA2
SCHEMBL3481666 0.80 ACHE (0.38) TSHRALDH1A1CES2CES1LMNA
SCHEMBL2783701 0.79
SCHEMBL3481968 0.78 TP53 (0.54) ALDH1A1KDM4ENPC1POLBRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1525 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080643-A High-flame-retardance insulating phenyl silicone rubber for electric power and preparation method thereof 2026-05-26 CN claimed
US-20260054429-A1 METHOD AND MATERIALS FOR MANUFACTURING HIGH-EFFICIENCY HEATING ENCLOSURES AND APPLIANCES UT BATTELLE LLC (US) 2026-02-26 US claimed
US-12384917-B1 Physical characteristics of polysilylether polymers in additive manufacturing of energetic materials THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 2025-08-12 US claimed
CN-118725573-B Dissolved oxygen fluorescent chemical sensing material and preparation and application thereof 东华大学 2025-05-16 CN claimed
CN-119978822-A Antistatic silicone rubber composition and preparation method thereof 杭州之江有机硅化工有限公司 2025-05-13 CN claimed
CN-119662118-A Sprayable heat-conducting silicone rubber and preparation method thereof 唐山三友化工股份有限公司 2025-03-21 CN claimed
CN-118006125-B Polyamic acid composition and modified polyamide acid 比亚迪股份有限公司 2025-03-11 CN claimed
CN-118745670-A Preparation method of active fire-extinguishing battery fireproof cover material 浙江葆润应用材料有限公司 2024-10-08 CN claimed
CN-118725573-A Dissolved oxygen fluorescent chemical sensing material and preparation and application thereof 东华大学 2024-10-01 CN claimed
CN-118724936-A Octamethyl hexaepoxy diphenyl heptasiloxane and preparation method thereof 武汉珈材科技有限公司 2024-10-01 CN claimed
US-5139816-A UV radiation curing of epoxy- or vinyl-functional diorganopolysiloxanes GENERAL ELECTRIC COMPANY (US) 1992-08-18 US claimed
US-4918040-A Polymerization of olefins PHILLIPS PETROLEUM COMPANY (US) 1990-04-17 US claimed
EP-0104374-B1 POLYMERIZATION OF OLEFINS PHILLIPS PETROLEUM COMPANY (US) 1988-05-04 EP claimed
US-4477586-A COORDINATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1984-10-16 US claimed
EP-0104374-A2 Polymerization of olefins PHILLIPS PETROLEUM COMPANY (US) 1984-04-04 EP claimed
US-4155864-A ENDCAPPED POLYDIMETHYLSILOXANE AND MINOR AMOUNT OF ANOTHER POLYSILOXANE; DIELECTRIC FLUIDS IN ELECTRICAL APPARATUS UNION CARBIDE CORPORATION (US) 1979-05-22 US claimed
US-4139403-A Dinitroalkyl and fluorodinitroalkyl silicon compounds THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) 1979-02-13 US claimed
US-4056492-A PROCESS FOR THE PRODUCTION OF A BODIED SILICONE RESIN WITHOUT THE USE OF A CATALYST GENERAL ELECTRIC COMPANY (US) 1977-11-01 US claimed
US-4001168-A Transparent storage-stable polysiloxanes which cross-link under atmospheric conditions BAYER AKTIENGESELLSCHAFT (DT) 1977-01-04 US claimed
US-3959563-A Method for rendering vitreous surfaces water repellant and dirt deposit resistant and articles produced thereby GENERAL ELECTRIC COMPANY (US) 1976-05-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260054429-A1 METHOD AND MATERIALS FOR MANUFACTURING HIGH-EFFICIENCY HEATING ENCLOSURES AND APPLIANCES SMCHD1, MSI2, SMC3 TSHR 4702/4885DAO 3699/4885NAPRT 4793/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.