SCHEMBL5597134

SCHEMBL5597134

CC(C)(C)C1=C(CC2=C(C(C)(C)C)c3ccccc3[CH]2)[CH]c2ccccc21

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.33
CYP2D6 P10635 2/20 0.33
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9120704 0.88
SCHEMBL5597135 0.73
SCHEMBL7923402 0.71 ALDH1A1 (0.34)
SCHEMBL5597075 0.68 CDC25A (0.35) LMNACYP2D6CYP1A2CYP3A4
SCHEMBL2863610 0.63 FGFR1 (0.34) LMNACYP2D6CYP1A2CYP3A4
SCHEMBL218144 0.63 MAP2K7 (0.33) LMNACYP2D6CYP1A2CYP3A4
SCHEMBL1030000 0.61 LMNA (0.41) LMNACYP2D6CYP1A2CYP3A4
SCHEMBL18426 0.61 ALDH1A1 (0.44) LMNACYP2D6CYP1A2CYP3A4
SCHEMBL2046204 0.60 ALDH1A1 (0.53) LMNACYP2D6CYP1A2
SCHEMBL2872380 0.60 SETD7 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1392742-B1 OLEFIN COPOLYMERS CONTAINING CYCLOPROPANE RINGS IN THE MAIN CHAIN UNIV DEGLI STUDI SALERNO (IT) 2007-08-15 EP claimed
EP-1392742-B1 OLEFIN COPOLYMERS CONTAINING CYCLOPROPANE RINGS IN THE MAIN CHAIN UNIV DEGLI STUDI SALERNO (IT) 2007-08-15 EP disclosed
EP-1392742-A1 OLEFIN COPOLYMERS CONTAINING CYCLOPROPANE RINGS IN THE MAIN CHAIN Universita' Degli Studi di Salerno (IT) 2004-03-03 EP disclosed
WO-2002098936-A1 OLEFIN COPOLYMERS CONTAINING CYCLOPROPANE RINGS IN THE MAIN CHAIN UNIVERSITA' DEGLI STUDI DI SALERNO (IT) 2002-12-12 WO disclosed
US-5459117-A Doubly-conformationally locked, stereorigid catalysts for the preparation of tactiospecific polymers MONTELL TECHNOLOGY COMPANY BV (NL) 1995-10-17 US disclosed