SCHEMBL6874673

SCHEMBL6874673

COC(=O)/C(C#N)=C/c1ccc(O)c(OC)c1

nearest known ligand 0.77

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.77
KMT2A Q03164 5/20 0.77
ALDH1A1 P00352 4/20 0.77
MAPT P10636 4/20 0.77
KLK7 P49862 2/20 0.68
CSNK2A1 P68400 5/20 0.67
KLK14 Q9P0G3 1/20 0.67
KLK5 Q9Y337 1/20 0.67
EGFR P00533 1/20 0.65
CA12 O43570 1/20 0.61
CA1 P00915 1/20 0.61
CA2 P00918 1/20 0.61
CA9 Q16790 1/20 0.61
PKM P14618 2/20 0.61
HTT P42858 1/20 0.61
CYP1A2 P05177 1/20 0.60
MAPK1 P28482 1/20 0.58
ADORA2A P29274 1/20 0.56
ADORA2B P29275 1/20 0.56
ADORA1 P30542 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6874677 1.00 MEN1 (0.77) MEN1KMT2AALDH1A1MAPTKLK7
SCHEMBL8604912 0.89 CYP1A2 (0.76) MEN1KMT2AALDH1A1MAPTKLK7
SCHEMBL8359618 0.89 CYP1A2 (0.76) MEN1KMT2AALDH1A1MAPTKLK7
SCHEMBL5328416 0.87 KMT2A (0.70) MEN1KMT2AALDH1A1MAPTKLK7
SCHEMBL5597271 0.87 KMT2A (0.70) MEN1KMT2AALDH1A1MAPTKLK7
SCHEMBL9347102 0.87 DNM1 (0.72) MEN1KMT2AALDH1A1MAPTEGFR
SCHEMBL9347097 0.87 DNM1 (0.72) MEN1KMT2AALDH1A1MAPTEGFR
SCHEMBL27587573 0.87 ALDH1A1 (0.70) MEN1KMT2AALDH1A1MAPTKLK7
SCHEMBL22897308 0.87 ALDH1A1 (1.00) MEN1KMT2AALDH1A1MAPTKLK7
SCHEMBL30883296 0.87 ALDH1A1 (1.00) MEN1KMT2AALDH1A1MAPTKLK7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100367110-C Chemical amplitude increased positive corrosionproof agent composition SUMITOMO CHEMICAL CO (JP) 2008-02-06 CN disclosed
US-6833421-B1 Compound ROLIC AG (CH) 2004-12-21 US disclosed
EP-1200494-B1 COMPOUND ROLIC AG (CH) 2004-08-18 EP disclosed
CN-1424625-A Chemical amplitude increased positive corrosionproof agent composition SUMITOMO CHEMICAL CO (JP) 2003-06-18 CN disclosed
EP-1200494-A1 COMPOUND Rolic AG (CH) 2002-05-02 EP disclosed
WO-2001007495-A1 COMPOUND ROLIC AG (CH) 2001-02-01 WO disclosed
EP-0555465-B1 RADIOGRAPHIC ELEMENT EASTMAN KODAK CO (US) 1998-04-01 EP disclosed
EP-0555465-A1 RADIOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (US) 1993-08-18 EP disclosed
EP-0555457-A1 RADIOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (US) 1993-08-18 EP disclosed
US-5215876-A Optical recording media has addition-condensation copolymer to reduce light transmission EASTMAN KODAK COMPANY (US) 1993-06-01 US disclosed
WO-1993005443-A1 RADIOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (US) 1993-03-18 WO disclosed
WO-1993005444-A1 RADIOGRAPHIC ELEMENT EASTMAN KODAK COMPANY (US) 1993-03-18 WO disclosed