Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.38 |
| ▸ | COPS5 | Q92905 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 5/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | MMP8 | P22894 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7546290 | 0.78 | MAPK1 (0.37) | PSMD14COPS5TP53MAPTCYP2D6 | |
| SCHEMBL5509833 | 0.78 | MAPT (0.36) | PSMD14COPS5TP53MAPTCYP2D6 | |
| SCHEMBL536400 | 0.77 | LMNA (0.37) | PSMD14COPS5TP53MAPTCYP2D6 | |
| Hydrochloric Acid SCHEMBL1072267 | 0.70 | CCR1 (0.40) | PSMD14COPS5TP53MAPTCYP2D6 | |
| SCHEMBL28517555 | 0.70 | KDM4E (0.54) | PSMD14COPS5TP53MAPTCYP2D6 | |
| SCHEMBL6131362 | 0.66 | LMNA (0.42) | PSMD14COPS5TP53MAPTCYP2D6 | |
| Hydrochloric Acid SCHEMBL1071469 | 0.65 | SMN1; SMN2 (0.43) | PSMD14COPS5TP53MAPTCYP2D6 | |
| SCHEMBL7547386 | 0.64 | LMNA (0.38) | PSMD14COPS5TP53MAPTCYP2D6 | |
| Hydrochloric Acid SCHEMBL1072120 | 0.64 | ALDH1A1 (0.43) | PSMD14COPS5TP53MAPTCYP2D6 | |
| SCHEMBL23308887 | 0.64 | PSMD14 (0.40) | PSMD14COPS5TP53MAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1740626-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | Basell Polyolefine GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005103099-A1 | CATALYST SYSTEM FOR OLEFIN POLYMERIZATION, ITS PRODUCTION AND USE | BASELL POLYOLEFINE GMBH (DE) | 2005-11-03 | — | — | WO | disclosed |