Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | CCR1 | P32246 | 3/20 | 0.35 |
| ▸ | CCR8 | P51685 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | CCR5 | P51681 | 2/20 | 0.35 |
| ▸ | GMNN | O75496 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28517555 | 0.66 | KDM4E (0.54) | LMNANPSR1ALDH1A1POLBSLC40A1 | |
| SCHEMBL6131362 | 0.65 | LMNA (0.42) | LMNANPSR1ALDH1A1POLBGAA | |
| SCHEMBL9186396 | 0.65 | CCR1 (0.58) | LMNANPSR1ALDH1A1POLBGAA | |
| SCHEMBL7546290 | 0.64 | MAPK1 (0.37) | LMNANPSR1ALDH1A1GAASLC40A1 | |
| SCHEMBL5509833 | 0.64 | MAPT (0.36) | LMNANPSR1ALDH1A1POLBGAA | |
| SCHEMBL5597461 | 0.64 | PSMD14 (0.38) | LMNAALDH1A1POLBSLC40A1KDM4E | |
| Hydrochloric Acid SCHEMBL1071469 | 0.64 | SMN1; SMN2 (0.43) | LMNAALDH1A1GAASLC40A1KDM4E | |
| SCHEMBL692866 | 0.64 | MMP2 (0.61) | LMNAALDH1A1SLC40A1KDM4EMAPT | |
| SCHEMBL29358836 | 0.64 | MMP2 (0.61) | LMNAALDH1A1SLC40A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL27944920 | 0.64 | CCR1 (0.56) | LMNANPSR1ALDH1A1POLBGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212333-A1 | MONOCYCLOPENTADIENYL COMPLEXES OF CHROMIUM, MOLYBDENUM OR TUNGSTEN WITH A DONOR BRIDGE | Basell Polyolefine GmbH (DE) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001012641-A1 | MONOCYCLOPENTADIENYL COMPLEXES OF CHROMIUM, MOLYBDENUM OR TUNGSTEN WITH A DONOR BRIDGE | BASELL POLYOLEFINE GMBH (DE) | 2001-02-22 | — | — | WO | disclosed |