Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5074095 | 0.78 | HSD11B1 (0.33) | — | |
| SCHEMBL8309553 | 0.72 | CHRM3 (0.36) | CHRM3 | |
| Hydrochloric Acid SCHEMBL4098130 | 0.69 | CHRM3 (0.34) | CHRM3 | |
| SCHEMBL12949141 | 0.65 | CHRM3 (0.37) | CHRM3 | |
| SCHEMBL12928650 | 0.64 | CHRM3 (0.36) | CHRM3 | |
| SCHEMBL12465180 | 0.63 | — | — | |
| SCHEMBL12083995 | 0.61 | ALDH1A1 (0.44) | CHRM3 | |
| SCHEMBL8313849 | 0.61 | CHRM3 (0.34) | CHRM3 | |
| SCHEMBL16196858 | 0.61 | — | — | |
| SCHEMBL7541983 | 0.61 | KMT2A (0.36) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268412-B8 | SULPHONAMIDO-SUBSTITUTED BRIDGED BICYCLOALKYL DERIVATIVES | MERCK SHARP & DOHME (GB) | 2007-02-21 | — | — | EP | disclosed |
| EP-1268412-A1 | SULPHONAMIDO-SUBSTITUTED BRIDGED BICYCLOALKYL DERIVATIVES | MERCK SHARP & DOHME LTD. (GB) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001070677-A1 | SULPHONAMIDO-SUBSTITUTED BRIDGED BICYCLOALKYL DERIVATIVES | MERCK SHARP & DOHME LIMITED (GB) | 2001-09-27 | — | — | WO | disclosed |