Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598024 | 1.00 | DPP4 (0.31) | DPP4RIPK1 | |
| SCHEMBL75974 | 0.75 | RIPK1 (0.33) | DPP4RIPK1 | |
| SCHEMBL22284346 | 0.74 | AGTR2 (0.38) | DPP4 | |
| SCHEMBL1810381 | 0.74 | NR1H2 (0.33) | DPP4RIPK1 | |
| SCHEMBL18322450 | 0.74 | RIPK1 (0.34) | DPP4RIPK1 | |
| SCHEMBL5597730 | 0.73 | CPN1 (0.37) | DPP4 | |
| SCHEMBL23924383 | 0.72 | — | — | |
| SCHEMBL20898987 | 0.72 | — | — | |
| SCHEMBL20702359 | 0.72 | RIPK1 (0.37) | DPP4RIPK1 | |
| SCHEMBL619575 | 0.72 | TYMP (0.33) | DPP4RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7265249-B2 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2007-09-04 | — | — | US | disclosed |
| US-20060189830-A1 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2006-08-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060189830-A1 | Enantioselective alpha-fluorination of aldehydes using chiral organic catalysts | ALDH3A1, ALDH1A1, POLL | DPP4 3317/4885RIPK1 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.