Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5598221 | 0.82 | PLAU (0.38) | ADRA1DADRA1AADRA1BDRD2DRD3 | |
| SCHEMBL6961088 | 0.69 | PLAU (0.47) | ADRA1DADRA1AADRA1BDRD1KDM4E | |
| SCHEMBL21890589 | 0.63 | SLC6A2 (0.45) | CYP2D6DRD3PRCP | |
| SCHEMBL13109615 | 0.63 | SLC6A2 (0.45) | CYP2D6DRD3PRCP | |
| SCHEMBL27670913 | 0.62 | CHEK1 (0.35) | DRD1KDM4EMAPTLMNAMEN1 | |
| SCHEMBL11035915 | 0.62 | SLC6A2 (0.36) | ADRA1DADRA1AADRA1BCYP2D6LMNA | |
| SCHEMBL4277150 | 0.62 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BDRD1KDM4E | |
| SCHEMBL30885125 | 0.62 | ATAD2 (0.47) | KDM4EMAPTHSD17B10TDP1LMNA | |
| SCHEMBL1708015 | 0.61 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BMAPTSIGMAR1 | |
| SCHEMBL22460911 | 0.61 | CYP1A2 (0.35) | KDM4ERAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007072041-A1 | THERAPEUTIC COMPOUNDS | ASTEX THERAPEUTICS LIMITED (GB) | 2007-06-28 | — | — | WO | disclosed |