Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | RGS12 | O14924 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29117084 | 0.69 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL29117081 | 0.69 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL29117066 | 0.69 | SIGMAR1 (0.43) | SIGMAR1 | |
| SCHEMBL4199458 | 0.67 | ADRA1D (0.57) | LMNAADRA1AOPRM1ADRA1DADRA1B | |
| SCHEMBL4026711 | 0.65 | SLC6A2 (0.66) | SLC6A2SLC6A4SLC6A3LMNAMAPK1 | |
| SCHEMBL29117072 | 0.65 | CES2 (0.37) | SLC6A2SLC6A4CYP1A2HTR2APOLB | |
| SCHEMBL28989831 | 0.64 | CYSLTR2 (0.38) | SLC6A2SLC6A4CYP1A2HTR2APOLB | |
| SCHEMBL30192016 | 0.64 | CES2 (0.36) | SLC6A2SLC6A4CYP1A2HTR2APOLB | |
| SCHEMBL11035918 | 0.62 | — | — | |
| SCHEMBL5598037 | 0.62 | ADRA1D (0.37) | LMNAADRA1ACYP2D6MEN1PMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537895-A | 4-PHENYL, 8-CARBONYLAMINO DERIVATIVES FOR CENTRAL NERVOUS SYSTEM DISORDERS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1985-08-27 | — | — | US | disclosed |