Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | PHGDH | O43175 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | FBP1 | P09467 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24378109 | 0.81 | MAPT (0.39) | MGLLPHGDHALDH1A1ALDH2 | |
| SCHEMBL5598157 | 0.81 | ALDH1A1 (0.35) | MGLLPHGDHALDH1A1ALDH2FBP1 | |
| SCHEMBL5598109 | 0.78 | TGM2 (0.32) | ALDH1A1 | |
| SCHEMBL24850960 | 0.78 | HSD11B1 (0.33) | ALDH1A1 | |
| SCHEMBL19577991 | 0.75 | TSHR (0.30) | MGLLFBP1 | |
| SCHEMBL17643519 | 0.75 | AKR1C3 (0.46) | MGLLPHGDHALDH1A1 | |
| SCHEMBL24134601 | 0.74 | ALOX15 (0.41) | — | |
| SCHEMBL17327849 | 0.72 | MGLL (0.31) | MGLLPHGDHALDH1A1ALDH2FBP1 | |
| SCHEMBL20663362 | 0.72 | MGLL (0.31) | MGLLPHGDHALDH1A1ALDH2FBP1 | |
| SCHEMBL20663345 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |