Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 7/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | BCL2 | P10415 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12971323 | 0.78 | MAPT (0.44) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| Water SCHEMBL28325022 | 0.77 | MAPT (0.43) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL6551078 | 0.71 | TDP1 (0.30) | TDP1 | |
| SCHEMBL5599148 | 0.69 | NPC1 (0.31) | ALDH1A1HSD17B10SMN1; SMN2HPGDNPC1 | |
| SCHEMBL4229470 | 0.69 | IDO1 (0.62) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28902030 | 0.68 | ALDH1A1 (0.36) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL28378706 | 0.67 | TDP1 (0.34) | ALDH1A1TP53TSHRSMN1; SMN2TDP1 | |
| SCHEMBL31450143 | 0.67 | TDP1 (0.36) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8419299 | 0.67 | TSHR (0.34) | MEN1KMT2ATSHR | |
| SCHEMBL11839093 | 0.66 | KDM4E (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385904-B1 | LOW-DENSITY SEALING MASS, GROUND MASS AND METHOD FOR PRODUCING THE SAME AND THE USE THEREOF | CHEMETALL GMBH (DE) | 2007-04-11 | — | — | EP | disclosed |