SCHEMBL8419299

SCHEMBL8419299

Oc1ccccc1C(c1ccccc1O)C(CCC1CO1)CC1CO1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.34
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11367565 0.70 TSHR (0.36) TSHRGABRA1GABRB2
SCHEMBL2273079 0.68 TSHR (0.38) TSHRGABRA1GABRB2MEN1KMT2A
SCHEMBL5599157 0.67 MAPT (0.39) TSHRMEN1KMT2A
SCHEMBL28487217 0.67 ALDH1A1 (0.30)
SCHEMBL1411674 0.66 TDP1 (0.43) TSHRGABRA1GABRB2MEN1KMT2A
SCHEMBL6551078 0.66 TDP1 (0.30)
SCHEMBL30194816 0.64 GABRA1 (0.62) TSHRGABRA1GABRB2MEN1KMT2A
SCHEMBL133407 0.64 GABRA1 (0.62) TSHRGABRA1GABRB2MEN1KMT2A
SCHEMBL10339410 0.64 GABRA1 (0.56) TSHRGABRA1GABRB2MEN1KMT2A
SCHEMBL3963673 0.63 GABRA1 (0.54) TSHRGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5962586-A Epoxy resin(s) with anhydride and polybutadiene-maleic anhydride adduct HARPER JOHN D (US) 1999-10-05 US disclosed
US-5629379-A Anhydride-hardened epoxy resin with polybutadiene-maleic anhydride adduct HARPER JOHN D (US) 1997-05-13 US disclosed