Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784831 | 0.80 | KMT2A (0.42) | GNRHR | |
| SCHEMBL5786885 | 0.79 | GNRHR (0.33) | GNRHR | |
| SCHEMBL5599768 | 0.78 | GNRHR (0.36) | GNRHR | |
| SCHEMBL5780824 | 0.77 | GNRHR (0.37) | GNRHR | |
| SCHEMBL5599105 | 0.76 | CHRNB2 (0.34) | GNRHR | |
| SCHEMBL5786887 | 0.76 | GNRHR (0.41) | GNRHR | |
| SCHEMBL5780422 | 0.76 | P2RX7 (0.36) | HPGDGNRHR | |
| SCHEMBL5599977 | 0.76 | GNRHR (0.34) | GNRHR | |
| SCHEMBL5788610 | 0.76 | GNRHR (0.34) | GNRHR | |
| SCHEMBL5599502 | 0.76 | GNRHR (0.32) | GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063745-A9 | NOVEL SPIROINDOLINE OR SPIROISOQUINOLINE COMPOUNDS, METHODS OF USE AND COMPOSITIONS THEREOF | ARENA PHARM INC (US) | 2007-02-01 | — | — | WO | claimed |