Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.61 |
| ▸ | SNCA | P37840 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.58 |
| ▸ | P4HB | P07237 | 1/20 | 0.57 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.52 |
| ▸ | TUBB | P07437 | 1/20 | 0.52 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.52 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.52 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.52 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.52 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.52 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.52 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.52 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.52 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599401 | 0.87 | DPP4 (0.67) | DPP4SNCAABCG2P4HBTNFRSF1A | |
| SCHEMBL28906356 | 0.80 | CTSL (0.62) | DPP4SNCAABCG2TNFRSF1A | |
| SCHEMBL4620096 | 0.79 | ABCG2 (0.74) | SNCAABCG2TNFRSF1ANR1H4ABCB1 | |
| SCHEMBL30428796 | 0.79 | ABCG2 (0.74) | SNCAABCG2TNFRSF1ANR1H4ABCB1 | |
| SCHEMBL4620101 | 0.79 | ABCG2 (0.74) | SNCAABCG2TNFRSF1ANR1H4ABCB1 | |
| SCHEMBL8066866 | 0.78 | ABCG2 (0.67) | ABCG2TNFRSF1ANR1H4ABCB1 | |
| SCHEMBL32681387 | 0.78 | TNFRSF1A (0.79) | ABCG2P4HBTNFRSF1AABCB1CXCL12 | |
| SCHEMBL5598882 | 0.78 | TNFRSF1A (0.79) | ABCG2P4HBTNFRSF1AABCB1CXCL12 | |
| SCHEMBL5598880 | 0.78 | TNFRSF1A (0.79) | ABCG2P4HBTNFRSF1AABCB1CXCL12 | |
| SCHEMBL28906366 | 0.78 | CHRNA7 (0.59) | ABCG2NR1H4MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115304513-A | Chalcone derivative with anti-inflammatory activity and synthesis method and application thereof | 湖北科技学院 | 2022-11-08 | — | — | CN | disclosed |