Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.56 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | RET | P07949 | 1/20 | 0.49 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.48 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3895337 | 0.94 | NOTUM (0.56) | NOTUMBAZ2BHPGDMEN1KMT2A | |
| SCHEMBL30561538 | 0.94 | NOTUM (0.56) | NOTUMBAZ2BHPGDMEN1KMT2A | |
| SCHEMBL2310023 | 0.91 | ALDH1A1 (0.55) | NOTUMBAZ2BHPGDMEN1KMT2A | |
| SCHEMBL14590719 | 0.88 | DPP7 (0.59) | NOTUMBAZ2BHPGDMEN1KMT2A | |
| SCHEMBL6499027 | 0.83 | ESR2 (0.69) | HPGDMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL396861 | 0.81 | HPGD (0.56) | BAZ2BHPGDMEN1KMT2ARAB9A | |
| SCHEMBL30875692 | 0.81 | HPGD (0.56) | BAZ2BHPGDMEN1KMT2ARAB9A | |
| SCHEMBL17797648 | 0.81 | HPGD (0.51) | HPGDMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL22145710 | 0.80 | DPP7 (0.54) | HPGDMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL20232216 | 0.79 | MAOA (0.50) | HPGDMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582616-B2 | Nucleoside transport inhibitors | QUESREMA ENTERPRISES LLC (US) | 2009-09-01 | — | — | US | disclosed |
| US-20070293444-A1 | Novel Nucleoside Transport Inhibitors | BUOLAMWINI JOHN K | 2007-12-20 | — | — | US | disclosed |
| WO-2007011290-A1 | Bronchorelaxing agents based on indol- and isoquinoline derivatives | RESPIRATORIUS AB (SE) | 2007-01-25 | — | — | WO | disclosed |
| EP-1708999-A1 | BRONCHORELAXING COMPOUNDS | RESPIRATORIUS AB (SE) | 2006-10-11 | — | — | EP | disclosed |
| US-20060040919-A1 | Bronchorelaxing compounds | RESPIRATORIUS AB (SE) | 2006-02-23 | — | — | US | disclosed |
| WO-2005070887-A1 | BRONCHORELAXING COMPOUNDS | RESPIRATORIUS AB (SE) | 2005-08-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060040919-A1 | Bronchorelaxing compounds | CHRM3, GPR3, CHRM2 | NOTUM 3316/4885BAZ2B 2791/4885HPGD 1383/4885 |
| US-20070293444-A1 | Novel Nucleoside Transport Inhibitors | SLC29A1, SLC29A2, SLC28A1 | NOTUM 4604/4885BAZ2B 3988/4885HPGD 1424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.