Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | GNRHR | P30968 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5599763 | 0.96 | DRD2 (0.38) | PTGDR2DRD2ALDH1A1L3MBTL1CHRM1 | |
| SCHEMBL5780226 | 0.90 | CDYL (0.35) | PTGDR2DRD2ALDH1A1L3MBTL1TP53 | |
| SCHEMBL5599828 | 0.86 | CHRM1 (0.38) | DRD2CHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL5600563 | 0.84 | TSHR (0.36) | PTGDR2DRD2ALDH1A1L3MBTL1CHRM1 | |
| SCHEMBL5599289 | 0.84 | DRD2 (0.37) | PTGDR2DRD2ALDH1A1L3MBTL1CHRM1 | |
| SCHEMBL5780173 | 0.83 | DRD2 (0.36) | PTGDR2DRD2ALDH1A1L3MBTL1CHRM1 | |
| SCHEMBL5783150 | 0.82 | PTGDR2 (0.36) | PTGDR2DRD2CHRM1CHRM3CHRM2 | |
| SCHEMBL5779582 | 0.82 | P2RX7 (0.41) | PTGDR2DRD2CHRM1CHRM3GNRHR | |
| SCHEMBL5782575 | 0.81 | GPR183 (0.34) | PTGDR2DRD2CHRM1CHRM3CHRM2 | |
| SCHEMBL5780283 | 0.81 | PTGDR2 (0.36) | PTGDR2DRD2CHRM1CHRM3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063745-A9 | NOVEL SPIROINDOLINE OR SPIROISOQUINOLINE COMPOUNDS, METHODS OF USE AND COMPOSITIONS THEREOF | ARENA PHARM INC (US) | 2007-02-01 | — | — | WO | claimed |