Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 2/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 3/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | FYN | P06241 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | MET | P08581 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28379581 | 0.84 | ALDH1A1 (0.42) | KDM4EACHEMAPT | |
| SCHEMBL28388592 | 0.82 | MAOA (0.44) | KDM4EHPGDACHETACR1ABL1 | |
| SCHEMBL1607613 | 0.81 | EGFR (0.44) | EGFRKDM4EADRB2PTPN1MAPK8 | |
| SCHEMBL30003701 | 0.81 | HTR1B (0.40) | ADRB2MAPTKCNA3 | |
| SCHEMBL30002666 | 0.80 | CYP1A2 (0.46) | KDM4EKCNA3 | |
| SCHEMBL20398542 | 0.78 | ACHE (0.38) | EGFRKDM4EHPGDACHETACR1 | |
| SCHEMBL5318913 | 0.78 | ACHE (0.38) | EGFRKDM4EHPGDACHETACR1 | |
| SCHEMBL28390368 | 0.76 | MAOA (0.45) | KDM4EHPGDACHEABL1MAPT | |
| SCHEMBL6934710 | 0.76 | SYK (0.48) | EGFRADRB2PTPN1MAPK8CHEK1 | |
| SCHEMBL22914881 | 0.73 | ADRB2 (0.48) | EGFRKDM4EHPGDADRB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1312605-B1 | Method for producing biaryl compounds | SUMITOMO CHEMICAL CO (JP) | 2007-04-25 | — | — | EP | disclosed |
| US-7122711-B2 | Method for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-17 | — | — | US | disclosed |
| US-20030158419-A1 | Method for producing biaryl compound | SUMITOMO CHEMICAL COMPANY, LIMITED | 2003-08-21 | — | — | US | disclosed |
| EP-1312605-A1 | Method for producing biaryl compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2003-05-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030158419-A1 | Method for producing biaryl compound | B2M, BMI1, CYP2W1 | EGFR 563/4885KDM4E 398/4885HPGD 3252/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.