Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.41 |
| ▸ | RELA | Q04206 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5781699 | 0.70 | GLA (0.39) | MAPTSMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL5599176 | 0.70 | GLA (0.39) | MAPTSMN1; SMN2NPC1KMT2AALDH1A1 | |
| SCHEMBL5578994 | 0.67 | MAPT (0.48) | MAPTSMN1; SMN2NPC1PKMNFKB1 | |
| Hydrochloric Acid SCHEMBL7007458 | 0.67 | NPY5R (0.49) | CYP3A4ALDH1A1CYP2D6 | |
| SCHEMBL5599757 | 0.65 | SIGMAR1 (0.40) | CYP2C19CYP3A4MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL5458965 | 0.63 | MAPT (0.79) | CYP2C19CYP3A4MAPTSMN1; SMN2NPC1 | |
| SCHEMBL31689287 | 0.62 | GFER (0.53) | MAPTSMN1; SMN2NPC1PKMNFKB1 | |
| SCHEMBL16860896 | 0.62 | KDM1A (0.37) | MAPK1 | |
| SCHEMBL5786199 | 0.61 | SIGMAR1 (0.43) | CYP2C19MAPTSMN1; SMN2PKMKMT2A | |
| SCHEMBL2801668 | 0.60 | NOTUM (0.40) | KMT2ACYP2D6P2RY1MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005063745-A9 | NOVEL SPIROINDOLINE OR SPIROISOQUINOLINE COMPOUNDS, METHODS OF USE AND COMPOSITIONS THEREOF | ARENA PHARM INC (US) | 2007-02-01 | — | — | WO | claimed |