Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5601238 | 0.89 | POLB (0.39) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5601407 | 0.85 | MEN1 (0.44) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL5599092 | 0.79 | KDM4E (0.34) | POLBMEN1KMT2AKDM4ELMNA | |
| SCHEMBL6647736 | 0.77 | KDM4E (0.37) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL5599079 | 0.74 | KMT2A (0.42) | MEN1KMT2AMAPTLMNA | |
| SCHEMBL5601356 | 0.74 | CHRNB2 (0.39) | POLBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL5599146 | 0.73 | OPRK1 (0.46) | POLBMEN1KMT2AKDM4EMAPT | |
| SCHEMBL6649435 | 0.72 | OPRK1 (0.37) | POLBMEN1KMT2AKDM4EOPRK1 | |
| SCHEMBL20204951 | 0.71 | CYP11B1 (0.45) | POLBMEN1KMT2AMAPTOPRK1 | |
| SCHEMBL6651103 | 0.70 | OPRK1 (0.36) | POLBMEN1KMT2AKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1746986-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005097099-A1 | ACTIVE SUBSTANCE COMBINATION COMPRISING A CARBINOL COMBINED TO AT LEAST AN NSAID | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2005-10-20 | — | — | WO | disclosed |