Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAF1 | P04049 | 14/20 | 0.43 |
| ▸ | BRAF | P15056 | 14/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | GPR183 | P32249 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5602958 | 0.82 | RAF1 (0.45) | RAF1BRAFPLAU | |
| SCHEMBL4781149 | 0.79 | PLAU (0.40) | RAF1BRAFPLAUMAPK14CFTR | |
| SCHEMBL4551368 | 0.73 | RAF1 (0.46) | RAF1BRAFPLAU | |
| SCHEMBL4783670 | 0.73 | MAPK14 (0.39) | RAF1BRAFPLAUMAPK14GPR183 | |
| SCHEMBL4782308 | 0.72 | PLAU (0.41) | RAF1BRAFPLAUMAPK14 | |
| SCHEMBL4782767 | 0.71 | CNR2 (0.42) | RAF1BRAFPLAUMAPK14 | |
| SCHEMBL5604506 | 0.71 | PLAU (0.40) | RAF1BRAFPLAU | |
| SCHEMBL5603871 | 0.71 | BRAF (0.41) | RAF1BRAFPLAU | |
| SCHEMBL4778219 | 0.70 | NAPEPLD (0.40) | RAF1BRAFPLAUMAPK14 | |
| SCHEMBL4781359 | 0.70 | ACKR3 (0.47) | RAF1BRAFPLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007075896-A2 | HETEROCYCLIC CYTOKINE INHIBITORS | KEMIA, INC. (US) | 2007-07-05 | — | — | WO | disclosed |