SCHEMBL5601733

SCHEMBL5601733

Cc1cc2c(c(C)c1C)[N]c1ccccc1S2

nearest known ligand 0.37

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.37
BACE1 P56817 1/20 0.31
NQO2 P16083 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601804 0.81 TRPA1 (0.38) TRPA1BACE1
SCHEMBL5600601 0.77 TRPA1 (0.40) TRPA1BACE1
SCHEMBL5602867 0.75 TRPA1 (0.35) TRPA1
SCHEMBL30004363 0.73 TRPA1 (0.50) TRPA1
SCHEMBL5602298 0.73 NQO2 (0.33) NQO2
SCHEMBL24828 0.72 TRPA1 (0.54) TRPA1BACE1
SCHEMBL3869329 0.69 TRPA1 (0.40) TRPA1BACE1NQO2
SCHEMBL5603569 0.67 TRPA1 (0.35) TRPA1
SCHEMBL3422095 0.66 MAOA (0.42) NQO2
SCHEMBL29120320 0.64 DRD2 (0.34) TRPA1BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
EP-1735354-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION Exxonmobil Chemical Company Inc. (US) 2006-12-27 EP disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed
WO-2005105864-A1 HETEROCYCLIC SUBSTITUTED METALLOCENE COMPOUNDS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2005-11-10 WO disclosed