SCHEMBL5602298

SCHEMBL5602298

Cc1cc2c(c(C)c1C)[N]c1ccccc1-2

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NQO2 P16083 1/20 0.33
RAB9A P51151 2/20 0.31
KDM4E B2RXH2 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
MAPT P10636 1/20 0.31
PKM P14618 1/20 0.31
KMT2A Q03164 1/20 0.31
NPC1 O15118 1/20 0.31
CASP3 P42574 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5601649 0.78 CYP1A2 (0.33) RAB9AKDM4EALDH1A1POLBMAPT
SCHEMBL5599881 0.74 RAB9A (0.38) RAB9AALDH1A1MAPTNPC1CASP3
SCHEMBL5601733 0.73 TRPA1 (0.37) NQO2
SCHEMBL5601896 0.72 HSD11B1 (0.31)
SCHEMBL5602257 0.72 NPC1 (0.41) RAB9AKDM4EALDH1A1PKMNPC1
SCHEMBL5603569 0.70 TRPA1 (0.35)
SCHEMBL51030 0.69 MEN1 (0.31) RAB9AMEN1MAPTKMT2ANPC1
SCHEMBL24062 0.68 MEN1 (0.37) RAB9AKDM4EMEN1ALDH1A1POLB
SCHEMBL5602449 0.68 HSD11B1 (0.40)
SCHEMBL5601789 0.67 NOS3 (0.34) RAB9AKDM4EALDH1A1MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed