SCHEMBL5602277

SCHEMBL5602277

c1ccc(Cc2cccc3c2[N]c2ccccc2O3)cc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.37
ELANE P08246 2/20 0.37
CTRC Q99895 3/20 0.36
CYP1A2 P05177 1/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2D6 P10635 1/20 0.36
CYP2C9 P11712 1/20 0.36
CYP2C19 P33261 1/20 0.36
CALM1 P0DP23 1/20 0.35
BCL2 P10415 1/20 0.35
BCL2L1 Q07817 1/20 0.35
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
MPO P05164 1/20 0.34
TRPA1 O75762 1/20 0.33
LOXL2 Q9Y4K0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5600589 0.85 EGFR (0.35) ELANEMEN1KMT2AGPR55
SCHEMBL5601488 0.79 MAOA (0.45) CYP1A2CYP2D6MEN1KMT2ATRPA1
SCHEMBL5602471 0.77 MAOA (0.36) ELANECYP1A2CYP2D6TRPA1
SCHEMBL5603742 0.76 HTR2A (0.39) HTR2AELANECYP1A2CYP3A4CYP2D6
SCHEMBL5600593 0.75 IDH1 (0.36) ELANECALM1GPR55
SCHEMBL5601859 0.74 LIPG (0.36) CYP3A4CYP2D6CYP2C9KMT2ATRPA1
SCHEMBL5601327 0.73 LIPG (0.41) BCL2L1
SCHEMBL5601908 0.73 CYP1A2 (0.40) CYP1A2CYP2D6TRPA1
SCHEMBL5602865 0.72 HTR2A (0.36) HTR2ACYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5603403 0.72 LIPG (0.44) BCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US claimed
US-7276567-B2 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-02 US disclosed
US-20050261449-A1 Heterocyclic substituted metallocene compounds for olefin polymerization EXXONMOBIL CHEMICAL PATENT INC. 2005-11-24 US disclosed